BEGIN:VCALENDAR METHOD:REQUEST PRODID:Microsoft Exchange Server 2010 VERSION:2.0 BEGIN:VTIMEZONE TZID:Eastern Standard Time BEGIN:STANDARD DTSTART:16010101T020000 TZOFFSETFROM:-0400 TZOFFSETTO:-0500 RRULE:FREQ=YEARLY;INTERVAL=1;BYDAY=1SU;BYMONTH=11 END:STANDARD BEGIN:DAYLIGHT DTSTART:16010101T020000 TZOFFSETFROM:-0500 TZOFFSETTO:-0400 RRULE:FREQ=YEARLY;INTERVAL=1;BYDAY=2SU;BYMONTH=3 END:DAYLIGHT END:VTIMEZONE BEGIN:VEVENT ORGANIZER;CN=MISM-Ops service;SENT-BY="mailto:aubriew@renci.org":mailto:mism- ops@duke.edu ATTENDEE;ROLE=REQ-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=mism-inte rnal@lists.renci.org:mailto:mism-internal@lists.renci.org ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN="Veronica Ciocanel, Ph.D.":mailto:veronica.ciocanel@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Griffin W oolley:mailto:griffin.woolley@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Nami Wada :mailto:nami.wada@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Judy Adki ns:mailto:judy.adkins@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Bobby Ni: mailto:bobby.ni@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Bruce Rog ers:mailto:bruce.rogers2@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Charles N unn:mailto:clnunn@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=cliburn.c han@duke.edu:mailto:cliburn.chan@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN="Dana Pasq uale, Ph.D.":mailto:dana.pasquale@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Danielle Burner:mailto:danielle.burner@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN="Georgia T omaras, Ph.D.":mailto:gdt@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN="Gina-Mari a Pomann, Ph.D.":mailto:gina-maria.pomann@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Grace McL aughlin:mailto:grace.mclaughlin@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Huan Lian g:mailto:huan.liang@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN="Jake Burc hard, Ph.D.":mailto:jake.burchard@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=James Moo dy:mailto:james.moody@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN="Janice Mc Carthy, Ph.D.":mailto:janice.mccarthy@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=zhicheng. ji:mailto:zhicheng.ji@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Jason Xu: mailto:jason.q.xu@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Jessica H ouse:mailto:jessica.house@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Jianfeng Lu:mailto:jianfeng.lu@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Jiazheng Miao:mailto:jiazheng.miao@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Jichun.xi e@duke.edu:mailto:Jichun.xie@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=John Hick ey:mailto:john.hickey@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN="Jonathan Li, Ph.D.":mailto:kan.li@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Jonathan Lin:mailto:jonathan.lin@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN="Justin Po llara, Ph.D.":mailto:jpollara@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=kapil.dev kota@duke.edu:mailto:kapil.devkota@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN="Kayla Kil patrick, Ph.D.":mailto:kayla.kilpatrick@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Kristine Glauber:mailto:kristine.glauber@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Lacey Ren de:mailto:lacey.rende@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN="Linh Do, Ph.D.":mailto:thuylinh.do@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Meghan Kw on:mailto:meghan.kwon@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Meredith Bailey:mailto:meredith.bailey@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN="Micah Luf tig, Ph.D.":mailto:micah.luftig@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN="Mieke van der Mescht, Ph.D.":mailto:mieke.vandermescht@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN="Moses Sek aran, Ph.D.":mailto:moses.sekaran@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=nrupen.bh avsar:mailto:nrupen.bhavsar@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN="R. Keith Reeves, Ph.D.":mailto:keith.reeves@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN="Rebecca N orth, Ph.D.":mailto:rebecca.thiem@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Richard B arfield:mailto:richard.barfield@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=rohit.sin gh@duke.edu:mailto:rohit.singh@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Rory Hend erson:mailto:rory.henderson@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN="Shweta Da mbal, Ph.D.":mailto:shweta.dambal@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Suchismit a Roy:mailto:suchismita.roy@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Timothy D urning:mailto:tim.durning@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN="Umar Qure shi, Ph.D.":mailto:muhammad.qureshi@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Zach Turn er:mailto:zach.turner@duke.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN="Conway, J essica Maral":mailto:jmc90@psu.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN="Gilani, I sma":mailto:igilani@renci.org ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN="Kebede, Y aphet":mailto:kebedey@renci.org ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Kevin Bry ant Flores:mailto:kbflores@ncsu.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN="Krishnamu rthy, Ashok Kumar":mailto:ashok@renci.org ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN=Melanie S adecki:mailto:msadeck@ncsu.edu ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN="Owen, Phi l":mailto:powen@renci.org ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN="Patel, Ha rit":mailto:hpatel@renci.org ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN="Roupe, Gr iffin Riley":mailto:groupe@renci.org ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN="Tyndall, Sarah":mailto:sarahtyndall@renci.org ATTENDEE;ROLE=OPT-PARTICIPANT;PARTSTAT=NEEDS-ACTION;RSVP=FALSE;CN="Weyhmille r, Aubrie Anne":mailto:aubriew@renci.org DESCRIPTION;LANGUAGE=en-US:\n\n\nFrom: mism-ops@duke.edu\nWhen: 10:00 - 11: 00 October 8\, 2026\nSubject: MISM Seminar Series - Eran Agmon [Hybrid]\nL ocation: https://duke.zoom.us/j/99104284020?jst=1\; Hock Plaza - Room #21 4 (CRTP Classroom)\n\n\nTitle: Compositional systems biology: An executabl e framework for connecting models across scales\n\nAbstract: Biological sy stems are organized across interacting scales\, from molecular networks an d metabolic pathways to cells\, tissues\, microbial communities\, and thei r environments\, yet many computational models remain difficult to connect \, reuse\, or extend beyond the scale or formalism for which they were ori ginally built. In this talk\, I will introduce Compositional Systems Biolo gy\, an approach for building multiscale biological models from interopera ble processes with explicit interfaces\, shared state representations\, an d well-defined orchestration patterns governing when and how model compone nts are executed. At the core of this work is Vivarium\, an open-source pl atform for multiscale simulation that integrates diverse modeling formalis ms -- including ODEs\, stochastic kinetics\, constraint-based models\, age nt-based dynamics\, and rule-based logic -- within a unified execution fra mework. I will describe how this framework has been used in whole-cell mod eling\, including vEcoli\, a comprehensive model of E. coli integrating me chanistic submodels of metabolism\, transcription\, translation\, macromol ecular synthesis\, and cell division\, and then discuss how the same compo sitional principles are being extended toward microbial systems\, host-mic robiome interactions\, and spatially resolved multicellular tissue models. Throughout the talk\, I will emphasize how executable composition can lin k biological structure to function\, support transparent model reuse and v alidation\, and create new opportunities for collaborative modeling across systems biology\, computational medicine\, and tissue-scale simulation.\n \nBio: Eran Agmon is an Assistant Professor at the University of Connectic ut School of Medicine and a member of the Center for Cell Analysis and Mod eling. His research focuses on software infrastructure and theory for comp ositional\, multiscale biological modeling\, motivated by a longstanding i nterest in cells as both integrated molecular systems and adaptive agents that function within\, respond to\, and reshape their environments. He is a Principal Investigator on DARPA’s Simulating Microbial Systems program \, where his group is developing hybrid simulations of E. coli that integr ate mechanistic\, agent-based\, and constraint-based models\, and a co-Inv estigator with the Center for Reproducible Biomedical Modeling\, contribut ing to community standards\, reusable simulation pipelines\, and infrastru cture for interoperable computational biology. His current work extends co mpositional modeling approaches to whole-cell simulation\, microbial syste ms in the ocean and gut\, and spatially resolved multicellular tissue mode ls. Dr. Agmon completed a postdoctoral fellowship at Stanford University\, where he worked on the E. coli whole-cell model\, and earned his PhD in I nformatics and Cognitive Science from Indiana University.\n\nZoom: https:/ /duke.zoom.us/j/99104284020?jst=1\nMeeting ID: 991 0428 4020\nLocation: Ho ck Plaza - Room #214 (CRTP Classroom)\n\n________________________________ \nThis seminar series is organized by the Center for Multiscale Immune Sys tems Modeling (MISM)\, funded by NIAID/NIH (U54A I191253).\n UID:040000008200E00074C5B7101A82E008000000000700117A2703DD01000000000000000 01000000051AE1FF04EC9B743AF157839C8D10DDD SUMMARY;LANGUAGE=en-US:FW: MISM Seminar Series - Eran Agmon [Hybrid] DTSTART;TZID=Eastern Standard Time:20261008T100000 DTEND;TZID=Eastern Standard Time:20261008T110000 CLASS:PUBLIC PRIORITY:5 DTSTAMP:20260625T154744Z TRANSP:OPAQUE STATUS:CONFIRMED SEQUENCE:2 LOCATION;LANGUAGE=en-US:https://duke.zoom.us/j/99104284020?jst=1\; Hock Pla za -  Room #214 (CRTP Classroom) X-MICROSOFT-CDO-APPT-SEQUENCE:2 X-MICROSOFT-CDO-OWNERAPPTID:2124855529 X-MICROSOFT-CDO-BUSYSTATUS:TENTATIVE X-MICROSOFT-CDO-INTENDEDSTATUS:BUSY X-MICROSOFT-CDO-ALLDAYEVENT:FALSE X-MICROSOFT-CDO-IMPORTANCE:1 X-MICROSOFT-CDO-INSTTYPE:0 X-MICROSOFT-DONOTFORWARDMEETING:FALSE X-MICROSOFT-DISALLOW-COUNTER:FALSE X-MICROSOFT-REQUESTEDATTENDANCEMODE:DEFAULT X-MICROSOFT-ISRESPONSEREQUESTED:FALSE X-MICROSOFT-LOCATIONDISPLAYNAME:https://duke.zoom.us/j/99104284020?jst=1\; Hock Plaza -  Room #214 (CRTP Classroom) X-MICROSOFT-LOCATIONSOURCE:None X-MICROSOFT-LOCATIONS:[{"DisplayName":"https://duke.zoom.us/j/99104284020?j st=1"\,"LocationAnnotation":""\,"LocationUri":""\,"LocationStreet":""\,"Lo cationCity":""\,"LocationState":""\,"LocationCountry":""\,"LocationPostalC ode":""\,"LocationFullAddress":""}\,{"DisplayName":"Hock Plaza -  Room #2 14 (CRTP Classroom)"\,"LocationAnnotation":""\,"LocationUri":""\,"Location Street":""\,"LocationCity":""\,"LocationState":""\,"LocationCountry":""\," LocationPostalCode":""\,"LocationFullAddress":""}] BEGIN:VALARM DESCRIPTION:REMINDER TRIGGER;RELATED=START:-PT15M ACTION:DISPLAY END:VALARM END:VEVENT END:VCALENDAR